Danio rerio ABC transporter genes abcb3 and abcb7 play a protecting role against metal contamination
ATP‐binding cassette (ABC) proteins are efflux transporters and some of them are involved in xenobiotic detoxification. The involvement of four zebrafish ABC transporters in cadmium, zinc and mercury detoxification was characterized in a metal hypersensitive mutant of Escherichia coli. The E. coli tolC mutant expressing ABCB3 or ABCB7 transporters exhibited higher survival ratios and lower metal accumulation under a metal exposure condition than the controls. For instance, in the presence of 8 and 10 μM of HgCl2, the survival ratios of bacteria expressing ABCB3 were four and six‐times higher than the control whereas the mercury concentrations were 2.5 and 2‐times lower than in the control. This work provides new data on the function of zebrafish ABCB3 and ABCB7 transporters and highlights their significance in metal detoxification
(Journal of Applied Toxicology. vol. 36, n° 0260-437X, pp. 1551-1557, 01/01/2016)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Long-term (1998-2010) large-scale comparison of the ecological quality status of gulf of lions (NW Mediterranean) benthic habitats
A comprehensive Mediterranean data set has been used to address 3 questions associated with the use of sensitivity/tolerance based biotic indices to infer the Ecological Quality status (EcoQs) of benthic habitats. Our results showed: (1) a significant effect of the reference database on derived sensitivity/tolerance measure (ES500.05) as well as associated Benthic Quality Index values and derived EcoQs; (2) a lack of correlation neither between BQI and AZTI Marine Biotic Index values nor between BQI and Multivariate-AZTI Marine Biotic Index values; (3) a lack of correlation between the values of the Benthic Habitat Quality Index (index derived from Sediment Profile Imagery) and those of either of the 3 tested biotic indices; and (4) a general agreement between the 3 tested biotic indices in describing the lack of global trend for the EcoQs of the Gulf of Lions despite the occurrence of significant changes in benthic macrofauna composition between 1998 and 2010. (C) 2015 Elsevier Ltd. All rights reserved.
(Marine Pollution Bulletin. vol. 102, n° 0025-326X, pp. 102--113, 01/01/2016)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, LECOB, OOB, UPMC, CNRS, UPMC, CNRS, CEAB, CSIC, IMBE, AU, AMU, CNRS, DIMAR, CNRS
Estuarine habitats structure zooplankton communities: Implications for the pelagic trophic pathways
Estuarine ecosystems have been described as a mosaic of habitats exhibiting different physical, biological and chemical properties and processes. These habitats are of primary importance for fishes, providing refuges and/or food for juveniles. While it is well known that habitats contribute also to the structuration of meio- and macrobenthic assemblages, this concept of habitat has never been associated to zooplankton communities, a major food resource for many pelagic fishes during summer in North-European estuaries. The objective of this work was thus to assess if estuarine habitats, in addition to the salinity gradient, structured zooplankton communities as well. Sampling was conducted at high tide during summer in a highly turbid system, the Gironde estuary, for which primary production and thus food resource at the basis of the food web is strongly limited. The results showed that even if the upstream-downstream estuarine gradient was the main factor structuring zooplankton at the scale of the estuary, there was a significant difference of zooplankton assemblages between samples collected over subtidal areas and those collected over intertidal areas. More particularly, the estuarine gradient was associated to the distribution pattern of species while difference between subtidal and intertidal samples were mainly due to difference in the level of abundance of species. Stable isotope analysis revealed that these zooplanktonic omnivorous species may be attracted to intertidal mudflats by microphytobenthos availability and that some planktivorous fishes, in particular Alosa fallax, preferentially fed on this zone. The role of intertidal habitats in structuring zooplankton assemblages suggests that this habitat strongly participates to the production of planktivorous species and that it represents a biotic vector of carbon resources toward subtidal areas. The loss of tidal flats habitats could thus have consequences on the functioning of pelagic system as well.
(Estuarine, Coastal and Shelf Science. vol. 179, n° 0272-7714, pp. 99-111, 26/04/2026)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, UR EABX, IRSTEA
Molecular and phenotypic responses of Japanese medaka (Oryzias latipes) early life stages to environmental concentrations of cadmium in sediment
Japanese medaka embryos were exposed to environmental concentrations of cadmium (Cd) to investigate adverse and adaptive responses in fish early life stages. Embryos were exposed during their whole development by static sediment-contact to environmental Cd concentrations (2 and 20 μg/g dry weight). Cd bioaccumulation, developmental defects, biochemical and biomolecular (qRT-PCR) responses were analyzed in embryos and hatchlings. A dose-dependent increase of Cd bioaccumulation and developmental defects was observed at hatching. Cd had clear impacts on heartbeat and cardiac morphogenesis and also induced to spinal deformities. The profile and the level of gene transcription were differentially modulated according to the Cd concentration, the duration of exposure and/or the developmental stage of fish. Pro-apoptotic bax and DNA repair rad51 transcripts were significantly repressed in embryos exposed to the highest Cd concentration. Repression of these genes was correlated to the increase of heart rate in 6-day-old embryos. NADH-dehydrogenase nd5 gene transcription was inhibited in larvae at the lowest concentration suggesting mitochondrial respiratory chain impairment, in association with Cd-induced teratogenicity. Finally, wnt1 gene was overexpressed indicating putative deregulation of Wnt signaling pathway, and suggested to be implied in the occurrence of some spinal and cardiac deformities. Results of this study permitted to propose some promising markers at the transcriptional and phenotypical level, responding to environmental concentrations of Cd. The present work also highlights the usefulness of the modified version of the medaka embryo-larval assay with sediment-contact exposure (MELAc) to investigate the toxicity and the modes of action of sediment-bound pollutants.
(Environmental Science and Pollution Research. vol. 23, n° 0944-1344, pp. 17969-17981, 26/04/2026)
SEBIO, INERIS, URCA, ULH, NU, URCA, CNRS, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
DYNALIT : Dynamique du Littoral et Trait de Côte
Le littoral, caractérisé par une grande diversitéd’environnements (plages sableuses ou rocheuses, cordonsdunaires, falaises, lagunes, estuaires...) est une zone très mobile etévolutive du fait de forçages hydrodynamiques et météorologiquessouvent intenses. Cet environnement est fragile, car soumis àl’impact d’activités humaines qui ne cessent d’augmenter (urbanisation,aménagements...), mais aussi aux effets du changementclimatique (élévation du niveau de la mer, modification durégime de houles, inondations). Comprendre le fonctionnementhydromorpho-sédimentaire des environnements littoraux est crucialpour prédire leur évolution et celle des écosystèmes associés.Le Service National d’Observation labellisé par le CNRS, (SNO)DYNALIT, - Dynamique du Littoral et du Trait de Côte a pourbut de constituer une base de données hydromorphologiques sur lelong terme de 29 sites ateliers représentatifs des environnementslittoraux français (côtes sableuses, falaises et embouchures) afin :- De mesurer la cinématique de ces environnements et du trait decôte associé ;- De mieux comprendre les interactions entre les processushydrodynamiques-transport sédimentaires-réponse morphologiqueassociés à la dynamique du littoral ;- Utiliser les observations pour améliorer notre connaissance desréponses de la morphologie des littoraux dans différents contextesde forçages météo-marins ;- D’utiliser ces observations pour analyser l’importance relativedes facteurs anthropiques et naturels sur la dynamique littorale ;- De se positionner en interlocuteur pour les responsables de ladéfinition et la mise en oeuvre des politiques de gestion des risqueslittoraux.
(pp. 84, 26/04/2026)
LDO, INSU - CNRS, UBO EPE, CNRS, LETG - Nantes, UNICAEN, NU, EPHE, PSL, UBO EPE, UR2, CNRS, IGARUN, UN, INSU - CNRS, UM, CNRS, UA, LIENSs, INSU - CNRS, ULR, CNRS, LETG - Caen, LETG, UNICAEN, NU, UA, EPHE, PSL, UBO EPE, UR2, CNRS, IGARUN, UN, LOMC, ULH, NU, CNRS, LOG, INSU - CNRS, ULCO, CNRS, IRD [Ile-de-France], ULCO, M2C, UNICAEN, NU, INSU - CNRS, UNIROUEN, NU, CNRS, GR, UR, INSU - CNRS, CNRS, Cerema Equipe-projet HA, Cerema, UPPA, LPG-ANGERS, LPG, UA, UN UFR ST, UN, INSU - CNRS, CNRS, IRD, UPVD, AU, UR, UM, UG, UA, GET, IRD, UT3, Comue de Toulouse, INSU - CNRS, CNES, CNRS, CEREGE, IRD, INRA, AMU, CdF (institution), INSU - CNRS, CNRS, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, LETG - Brest, LETG, UNICAEN, NU, UA, EPHE, PSL, UBO EPE, UR2, CNRS, IGARUN, UN
Improving past sea surface temperature reconstructions from the Southern Hemisphere oceans using planktonic foraminiferal census data
We present an improved database of planktonic foraminiferal census counts from the Southern Hemisphere oceans (SHO) from 15°S to 64°S. The SHO database combines three existing databases. Using this SHO database, we investigated dissolution biases that might affect faunal census counts. We suggest a depth/ math formula threshold of ~3800 m/ math formula = ~ −10 to −5 µmol/kg for the Pacific and Indian Oceans and ~4000 m/ math formula = ~0 to 10 µmol/kg for the Atlantic Ocean, under which core-top assemblages can be affected by dissolution and are less reliable for paleo-sea surface temperature (SST) reconstructions. We removed all core tops beyond these thresholds from the SHO database. This database has 598 core tops and is able to reconstruct past SST variations from 2° to 25.5°C, with a root mean square error of 1.00°C, for annual temperatures. To inspect how dissolution affects SST reconstruction quality, we tested the data base with two “leave-one-out” tests, with and without the deep core tops. We used this database to reconstruct summer SST (SSST) over the last 20 ka, using the Modern Analog Technique method, on the Southeast Pacific core MD07-3100. This was compared to the SSST reconstructed using the three databases used to compile the SHO database, thus showing that the reconstruction using the SHO database is more reliable, as its dissimilarity values are the lowest. The most important aspect here is the importance of a bias-free, geographic-rich database. We leave this data set open-ended to future additions; the new core tops must be carefully selected, with their chronological frameworks, and evidence of dissolution assessed.
(Paleoceanography. vol. 31, n° 0883-8305, pp. 822-837 (IF 3,738), 26/04/2026)
LSCE, UVSQ, INSU - CNRS, CNRS, DRF (CEA), CEA, GEOPS, UP11, CNRS, PALEOCEAN, LSCE, UVSQ, INSU - CNRS, CNRS, DRF (CEA), CEA, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, NIWA
Comment réduire l'impact des rejets urbains d'une agglomération sur le milieu récepteur ? Retours sur les résultats du programme Etiage et sur la prise en compte progressive de la qualité dans le mode de gestion de Bordeaux Métropole
Pour répondre aux ambitions de Bordeaux Métropole et l'accompagner dans la reconquête d'un état écologique acceptable de l'estuaire, un consortium s'est formé autour du programme Etiage. Ce programme a permis d'expliciter les facteurs responsables de la qualité biogéochimique de la Gironde.
(TSM. Techniques Sciences Méthodes – Génie urbain, génie rural, n° 0299-7258, pp. 79-97, 26/04/2026)
IRSTEA, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, UR EABX, IRSTEA, IRSTEA
Sea surface temperature variability in the North Western Mediterranean Sea (Gulf of Lion) during the Common Era
This study investigates the multidecadal-scale variability of sea surface temperatures (SSTs) in the convection region of the Gulf of Lion (NW Mediterranean Sea) over the full past 2000 yr (Common Era) using alkenone biomarkers. Our data show colder SSTs by 1.7 °C over most of the first millennium (200–800 AD) and by 1.3 °C during the Little Ice Age (LIA; 1400–1850 AD) than the 20th century mean (17.9 °C). Although on average warmer, those of the Medieval Climate Anomaly (MCA) (1000–1200 AD) were lower by 1 °C. We found a mean SST warming of 2 °C/100 yr over the last century in close agreement with the 0.22 and 0.26 °C/decade values calculated for the western Mediterranean Sea from in situ and satellite data, respectively. Our results also reveal strongly fluctuating SSTs characterized by cold extremes followed by abrupt warming during the LIA. We suggest that the coldest decades of the LIA were likely caused by prevailing negative EA states and associated anticyclone blocking over the North Atlantic resulting in cold continental northeasterly winds to blow over Western Europe and the Mediterranean region.
(Earth and Planetary Science Letters. vol. 456, n° 0012-821X, pp. 124-133, 26/04/2026)
BTP, LOCEAN, IPSL, ENS-PSL, UVSQ, UPMC, CEA, INSU - CNRS, X, CNES, CNRS, MNHN, IRD, UPMC, INSU - CNRS, CNRS, LOCEAN, IPSL, ENS-PSL, PSL, UVSQ, UPMC, CEA, INSU - CNRS, X, IP Paris, CNES, CNRS, MNHN, IRD, UPMC, INSU - CNRS, CNRS, CSIC, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, CEFREM, UPVD, INSU - CNRS, CNRS
Relation entre hypoxie, émissions de GES et force du vent dans les herbiers denses d’hydrophytes dans les lacs
L’impact de deux hydrophytes exotiques, Lagarosiphon major et Egeria densa, sur la biogéochimie d’un lac tempéré peu profond (lac de Lacanau - Aquitaine, SO France) a été étudié pendant 3 ans (2013-2015). Les résultats montrent qu’une biomasse élevée de plantes favorise la stratification de la colonne d’eau et l’accumulation de la matière organique, avec des rétroactions positives sur les processus de respiration anaérobie. En même temps, la canopée des plantes semble agir comme un filtre, en favorisant l’oxydation du méthane rejeté à l’interface sédiment-eau. Au contraire, lors des fréquents évènements de brassage dus au vent, quand la colonne d’eau est mélangée et entièrement oxygénée, le méthane est probablement rapidement émis vers l’atmosphère. Cette étude montre qu’il existe une interaction non négligeable entre l’hydrodynamique, l’écophysiologie des plantes et le cycle du carbone. Des recherches supplémentaires sur ces processus sont donc nécessaires dans le contexte des changements globaux que subissent ces lacs.
(pp. 15, 26/04/2026)
UR EABX, IRSTEA, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
The French initiative for scientific cores virtual curating : a user-orientedintegrated approach
Managing scientific data is probably one the most challenging issue in modern science. The question is made evenmore sensitive with the need of preserving and managing high value fragile geological sam-ples: cores. Largeinternational scientific programs, such as IODP or ICDP are leading an intense effort to solve this problem andpropose detailed high standard work- and dataflows thorough core handling and curating. However most resultsderived from rather small-scale research programs in which data and sample management is generally managedonly locally – when it is . . .The national excellence equipment program (Equipex) CLIMCOR aims at developing French facilities for coringand drilling investigations. It concerns indiscriminately ice, marine and continental samples. As part of this initiative,we initiated a reflexion about core curating and associated coring-data management. The aim of the project isto conserve all metadata from fieldwork in an integrated cyber-environment which will evolve toward laboratoryacquireddata storage in a near future. In that aim, our demarche was conducted through an close relationship withfield operators as well laboratory core curators in order to propose user-oriented solutions.The national core curating initiative currently proposes a single web portal in which all scientifics teams can storetheir field data. For legacy samples, this will requires the establishment of a dedicated core lists with associatedmetadata. For forthcoming samples, we propose a mobile application, under Android environment to capture technicaland scientific metadata on the field. This application is linked with a unique coring tools library and is adaptedto most coring devices (gravity, drilling, percussion, etc...) including multiple sections and holes coring operations.Those field data can be uploaded automatically to the national portal, but also referenced through internationalstandards or persistent identifiers (IGSN, ORCID and INSPIRE) and displayed in international portals (currently,NOAA’s IMLGS).In this paper, we present the architecture of the integrated system, future perspectives and the approach we adoptedto reach our goals. We will also present in front of our poster, one of the three mobile applications, dedicated moreparticularly to the operations of continental drillings.
(26/04/2026)
EDYTEM, USMB [Université de Savoie] [Université de Chambéry], CNRS, Fédération OSUG, DTI, INSU - CNRS, CNRS, ISTerre, IFSTTAR, INSU - CNRS, USMB [Université de Savoie] [Université de Chambéry], CNRS, UGA [2016-2019], EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, LGGE, INSU - CNRS, CNRS, OSUG, Grenoble INP, INSU - CNRS, IRSTEA, USMB [Université de Savoie] [Université de Chambéry], CNRS, UGA [2016-2019], EMBS, iSTeP, UPMC, CNRS, IRSI, IFREMER, INSU - CNRS