Danio rerio ABC transporter genes abcb3 and abcb7 play a protecting role against metal contamination
ATP‐binding cassette (ABC) proteins are efflux transporters and some of them are involved in xenobiotic detoxification. The involvement of four zebrafish ABC transporters in cadmium, zinc and mercury detoxification was characterized in a metal hypersensitive mutant of Escherichia coli. The E. coli tolC mutant expressing ABCB3 or ABCB7 transporters exhibited higher survival ratios and lower metal accumulation under a metal exposure condition than the controls. For instance, in the presence of 8 and 10 μM of HgCl2, the survival ratios of bacteria expressing ABCB3 were four and six‐times higher than the control whereas the mercury concentrations were 2.5 and 2‐times lower than in the control. This work provides new data on the function of zebrafish ABCB3 and ABCB7 transporters and highlights their significance in metal detoxification
(Journal of Applied Toxicology. vol. 36, n° 0260-437X, pp. 1551-1557, 01/01/2016)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Validation and uncertainties evaluation of an isotope dilution-SPE-LC–MS/MS for the quantification of drug residues in surface waters
The present work describes the development and validation of a reference method conducted at the French National Institute of Metrology (LNE) for the quantitative determination of psychoactive compounds in the dissolved fraction of surface waters. More specifically an isotope dilution-SPE-LC-MS/MS based method has been implemented for the characterization of a broad range of analytes belonging to different classes of psychotropic drugs such as benzodiazepines, antidepressants, stimulants, opiates and opioids, anticonvulsants, anti-dementia drugs, analgesics as well as the anti-inflammatory drug diclofenac in the low ng L(-1) range of concentration. Full validation of the method was performed following procedures described by the French standard NF T90-210. Limits of quantification between 0.14 and 3.54 ng L(-1) were obtained. Method recoveries from 71 to 123% were observed with standard deviation below 10% in intermediate precision conditions. Accuracy was determined for every compound: measurement errors were between -4 and +1% and standard deviations in intermediate precision conditions were included within a 1-9% interval. Finally, measurement uncertainties were evaluated following the Guide to the expression of uncertainty in measurement (GUM). Expanded uncertainties (k=2) ranged from 2% for carbamazepine, EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine) and venlafaxine to 17% for diazepam. The validated method was implemented to Seine river surface waters demonstrating its fitness for purpose. All compounds were detected and 22 out of 25 analytes were quantified. More specifically, measured concentration ranged from 0.39 ng L(-1) for MDMA (3,4-methylene-dioxy-N-methylamphetamine) to 182 ng L(-1) for gabapentine.
(Talanta. vol. 146, n° 0039-9140, pp. 138-147, 01/01/2016)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Long-term (1998-2010) large-scale comparison of the ecological quality status of gulf of lions (NW Mediterranean) benthic habitats
A comprehensive Mediterranean data set has been used to address 3 questions associated with the use of sensitivity/tolerance based biotic indices to infer the Ecological Quality status (EcoQs) of benthic habitats. Our results showed: (1) a significant effect of the reference database on derived sensitivity/tolerance measure (ES500.05) as well as associated Benthic Quality Index values and derived EcoQs; (2) a lack of correlation neither between BQI and AZTI Marine Biotic Index values nor between BQI and Multivariate-AZTI Marine Biotic Index values; (3) a lack of correlation between the values of the Benthic Habitat Quality Index (index derived from Sediment Profile Imagery) and those of either of the 3 tested biotic indices; and (4) a general agreement between the 3 tested biotic indices in describing the lack of global trend for the EcoQs of the Gulf of Lions despite the occurrence of significant changes in benthic macrofauna composition between 1998 and 2010. (C) 2015 Elsevier Ltd. All rights reserved.
(Marine Pollution Bulletin. vol. 102, n° 0025-326X, pp. 102--113, 01/01/2016)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, LECOB, OOB, UPMC, CNRS, UPMC, CNRS, CEAB, CSIC, IMBE, AU, AMU, CNRS, DIMAR, CNRS
Spatial distribution and toxic potency of trace metals in surface sediments of the Seine estuary (France)
Due to very high anthropogenic pressures and urban waste discharge, the Seine estuary is still among the world's most polluted estuaries. The purpose of this work is to investigate the distribution of trace metals in surface sediments in order to assess to the contamination level, metal bioavailability, and ecotoxicological status. Five sites covering the salinity gradient of the estuary were chosen to evaluate the distribution and contamination level of trace metals in surface sediments. The results showed that trace metal concentration varied seasonally and spatially. Subsequently to assess the actual environmental toxicity of sediments, the Microtox® Bioassay using Vibrio fischeri was applied on aqueous extract of sediment. Calculated enrichment factors revealed that these sediments were highly polluted by mercury, cadmium, zinc, and lead. Most of pollution sources are localized upstream especially in Poses and Oissel, and the contamination levels decreased from Poses to north mudflat site. Positive values of toxicity index were detected in the upstream sediments indicating potential bioavailability of trace metals in the sediments. Sediment toxicity measured with the Microtox® test was positively correlated with toxicity index demonstrating the usefulness of the toxicity index for sediment quality assessment and possible implication of metals in sediment toxicity.
(CLEAN - Soil, Air, Water. vol. 43, n° 1863-0650, pp. 1 -9, 25/10/2026)
FSP III, LU / ULB, LASIRE, INC-CNRS, CNRS, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Stable isotope ratios in bentho-demersal biota along a depth gradient in the Bay of Biscay: A multitrophic study
Although stable isotope ratios are increasingly used to investigate the trophic ecology of marine organisms, their spatial variations are still poorly understood in the coastal environment. In this study, we measured the stable isotope composition (delta C-13, delta N-15) of suspended particulate organic matter (SPOM) (primary producer), a suspension feeder, the great scallop Pecten maximus (primary consumer), megabenthic decapods and benthic fishes (secondary consumers) along a depth gradient (from 5 m to 155 m depth) across the continental shelf of the Bay of Biscay. Although the three trophic levels exhibited similar delta C-13 patterns along the gradient, the delta N-15 patterns varied between SPOM, scallops and carnivores. The delta N-15 difference between SPOM and scallops decreased with increasing depth, suggesting that non trophic factors may affect the stable isotope composition of scallops at deepest sampling stations. An opposed trend was found between scallops and carnivores, suggesting that the trophic level of these carnivores increased at higher depth, possibly as an adaptation to lower prey abundances. Although our results suggest that primary consumers are suitable to establish isotopic baselines in coastal environments, we stress the need for further studies aiming at characterizing the variability of stable isotopes in coastal biota, and the respective effects of baseline, trophic and metabolic factors in their isotopic composition.
(Estuarine, Coastal and Shelf Science. vol. 179, n° 0272-7714, pp. 201-206, 25/10/2026)
LEMAR, IRD, IFREMER, UBO EPE, CNRS, IRD, UBO EPE, CNRS, LIENSs, INSU - CNRS, ULR, CNRS, EMH, IFREMER, IUEM, IRD, INSU - CNRS, UBO EPE, CNRS, ESE, INRA, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
The Ponto-Caspian basin as a final trap for southeastern Scandinavian Ice-Sheet meltwater
This paper provides new data on the evolution of the Caspian Sea and Black Sea from the Last Glacial Maximum until ca. 12 cal kyr BP. We present new analyses (clay mineralogy, grain-size, Nd isotopes and pollen) applied to sediments from the river terraces in the lower Volga, from the middle Caspian Sea and from the western part of the Black Sea. The results show that during the last deglaciation, the Ponto-Caspian basin collected meltwater and fine-grained sediment from the southern margin of the Scandinavian Ice Sheet (SIS) via the Dniepr and Volga Rivers. It induced the deposition of characteristic red-brownish/chocolate-coloured illite-rich sediments (Red Layers in the Black Sea and Chocolate Clays in the Caspian Sea) that originated from the Baltic Shield area according to Nd data. This general evolution, common to both seas was nevertheless differentiated over time due to the specificities of their catchment areas and due to the movement of the southern margin of the SIS. Our results indicate that in the eastern part of the East European Plain, the meltwater from the SIS margin supplied the Caspian Sea during the deglaciation until ∼13.8 cal kyr BP, and possibly from the LGM. That led to the Early Khvalynian transgressive stage(s) and Chocolate Clays deposition in the now-emerged northern flat part of the Caspian Sea (river terraces in the modern lower Volga) and in its middle basin. In the western part of the East European Plain, our results confirm the release of meltwater from the SIS margin into the Black Sea that occurred between 17.2 and 15.7 cal kyr BP, as previously proposed. Indeed, recent findings concerning the evolution of the southern margin of the SIS and the Black Sea, show that during the last deglaciation, occurred a westward release of meltwater into the North Atlantic (between ca. 20 and 16.7 cal kyr BP), and a southward one into the Black Sea (between 17.2 and 15.7 cal kyr BP). After the Red Layers/Chocolate Clays deposition in both seas and until 12 cal kyr BP, smectite became the dominant clay mineral. The East European Plain is clearly identified as the source for smectite in the Caspian Sea sediments. In the Black Sea, smectite originated either from the East European Plain or from the Danube River catchment. Previous studies consider smectite as being only of Anatolian origin. However, our results highlight both, the European source for smectite and the impact of this source on the depositional environment of the Black Sea during considered period.
(Quaternary Science Reviews. vol. 148, n° 0277-3791, pp. 29-43 (IF 4,521), 25/10/2026)
GEOPS, UP11, CNRS, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, GM, IFREMER, RMCA
Heteromysis (Heteromysis) microps (Crustacea, Mysidae), a commensal species for Upogebia pusilla (Crustacea, Upogebiidae) in Arcachon Bay (NE Atlantic Ocean)
Background: The mysid Heteromysis (Heteromysis) microps is reported for the first time in the Bay of Biscay. During surveys carried out between March and September 2015 in Arcachon Bay, mysid specimens were fortuitously collected from Upogebia pusilla burrows. Results: Details on morphology, colour pattern and behaviour of H. microps are provided. Conclusions: Commensalism was frequently mentioned for Heteromysis species but never reported for H. microps. In this study, commensalism seems to be proved between the mysid and its host U. pusilla.
(Marine Biodiversity Records. vol. 9, n° 1755-2672, pp. 14, 25/10/2026)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Shoreline-Sandbar Dynamics at a High-Energy Embayed and Structurally-Engineered Sandy Beach: Anglet, SW France
Anglet beach, Basque Coast (SW France), is a 4-km long embayment bounded by a prominent headland in the South and by the southern Adour River training wall in the North. The beach is structurally-engineered with, within the embayment, 6 groins and 3 distinct sectors where the beach is backed by a seawall. The beach is high-energy intermediate, mostly double-barred, composed of medium to coarse sand with a steep beach face (∼1/10). In January 2013, a video system was installed at the Southern end of Anglet beach at about 70 m above mean sea level to monitor about 2 km of the southern beach of Anglet that includes 4 groins extending about 100 m seaward and a 1- km seawall backing the beach. The study period includes the winter 2013/2014 that was outstanding in terms of the available energy arriving at the coast with a 2-month-averaged significant wave height peaking at 3.6 m. Despite the extreme storm wave conditions during the winter 2013/2014, the outer bar crescentic patterns maintained and even further developed. The beach eroded by O(10 m) and, surprisingly and in contrast with the nearby northern open beaches, they recovered to their pre-winter 2013/2014 state within only a few months. Overall, Anglet beach appears to respond predominantly at individual storm frequency rather than at seasonal timescales, with the groins and headland acting as major controlling boundaries influencing beach state and dictating rip channel locations. \textcopyright Coastal Education and Research Foundation, Inc. 2016.
(Journal of Coastal Research. vol. 1, n° 0749-0208, pp. 393-397, 25/10/2026)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, SIAME, UPPA
Elimination de micropolluants prioritaires et émergents des eaux résiduaires urbaines par les bioréacteurs à membranes immergées (BRM). Rapport final de l’action 34
La technologie de traitement des eaux usées domestiques par bioréacteurs à membranes (BRM) immergées se développe fortement en France pour équiper les stations de traitement des eaux usées domestiques. La présente étude vise à déterminer les avantages des BRM vis-à-vis de l’élimination des substances prioritaires et émergentes. Dans ce but, des campagnes d’échantillonnage ont été réalisées par temps sec sur trois installations équipées de bioréacteurs à membranes à fibres creuses ou bien à membranes planes. Des expérimentations en réacteur séparé (boues dopées en micropolluants placées en conditions contrôlées) ont permis de préciser les processus de sorption et de biodégradation des micropolluants, en vue d’une modélisation de l’élimination. Au total, 24 métaux et 66 substances organiques ont été analysés (hydrocarbures aromatiques polycycliques, alkylphénols, pesticides, substances pharmaceutiques et hormones) par des méthodes analytiques robustes et sensibles. Les rendements de la file Eau ont été déterminés pour 61 micropolluants : 43 micropolluants ont été bien à très bien éliminés de l'eau (> 70%, voire > 90%), dont le cuivre, le plomb, le chrome, le nickel, le zinc, ainsi que plusieurs HAP, alkylphénols, médicaments et hormones, soit par piégeage des matières en suspension et transfert dans les boues, soit par biodégradation. 26 micropolluants ont été partiellement à faiblement éliminés (< 70%, voire < 30%), dont l’arsenic et le cadmium, ainsi que plusieurs micropolluants organiques y compris 7 médicaments (propranolol, sotalol, roxithromycine, sulfaméthoxazole), fluoxétine, diclofénac, carbamazépine) et le diuron. La présente étude démontre que les BRM induisent une élimination supplémentaire pour 22 micropolluants par rapport aux procédés conventionnels comme les boues activées aération prolongée, mais ce gain d’élimination est faible (< 20%). Ce gain concerne certains des micropolluants généralement adsorbés aux matières en suspension (ex. certains métaux ou HAP), et quelques médicaments (i.e., sotalol, roxithromycine, propranolol, timolol). Pour 38 autres micropolluants (en particulier pour les hormones, les détergents et la majorité des pharmaceutiques d’origine domestique notamment le diclofénac), les performances d'élimination par les BRM sont similaires à celles des boues activées aération prolongée fonctionnant à charges massiques appliquées équivalentes (sous-chargées). Un modèle cinétique a été développé, et simule correctement les concentrations de 51 micropolluants dans les rejets de BRM. Nous estimons qu’une faible augmentation du rendement serait possible (jusqu’à 15 unités supplémentaires) pour 6 micropolluants seulement, ceci en augmentant la concentration en matières en suspension dans les BRM. Pour diminuer les concentrations des micropolluants les plus réfractaires (non adsorbables et/ou non biodégradables) dans les rejets, les actions de réduction à la source ou la mise en place de traitement complémentaire sont donc indispensables, même pour les STEU équipées de BRM.
(pp. 105, 25/10/2026)
UR MALY, IRSTEA, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, UB
Remobilisation des radionucléides sous forme d’aérosols primaires et secondaires par vent faible à partir de couverts naturels (projet REMORA) : une nouvelle voie de transfert vers l’atmosphère
(25/10/2026)
IRSN, UMR ISPA, INRA, Bordeaux Sciences Agro, IRCELYON, UCBL, INC-CNRS, CNRS, BFP, INRA, UB, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS