Role of the microtubule-associated TPPP/p25 in Parkinson’s and related diseases and its therapeutic potential
(Expert Review of Proteomics. vol. 14, n° 1478-9450, pp. 301-309, 17/02/2017)
IC2MP [Poitiers], UP, INC-CNRS, CNRS, UCCS, UA, INC-CNRS, CNRS, CTAS, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, MTA
A new climate index controlling winter wave activity along the Atlantic coast of Europe: The West Europe Pressure Anomaly
A pioneering and replicable method based on a 66-year numerical weather and wave hindcast is developed to optimize a climate index based on the sea level pressure (SLP) that best explains winter wave height variability along the coast of western Europe, from Portugal to UK (36–52 ∘ N). The resulting so-called Western Europe Pressure Anomaly (WEPA) is based on the sea level pressure gradient between the stations Valentia (Ireland) and Santa Cruz de Tenerife (Canary Islands). The WEPA positive phase reflects an intensified and southward shifted SLP difference between the Icelandic low and the Azores high, driving severe storms that funnel high-energy waves toward western Europe southward of 52 ∘ N. WEPA outscores by 25–150% the other leading atmospheric modes in explaining winter-averaged significant wave height, and even by a largest amount the winter-averaged extreme wave heights. WEPA is also the only index capturing the 2013/2014 extreme winter that caused widespread coastal erosion and flooding in western Europe.
(Geophysical Research Letters. vol. 44, n° 0094-8276, pp. 1384 - 1392, 16/02/2017)
UB, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, LETG - Brest, LETG, UNICAEN, NU, UA, EPHE, PSL, UBO EPE, UR2, CNRS, IGARUN, UN
The Eye of the Medusa: XRF Imaging Reveals Unknown Traces of Antique Polychromy
(Analytical Chemistry. vol. 89, n° 0003-2700, pp. 1493-1500, 07/02/2017)
LAMS, UPMC, INC-CNRS, SU, CNRS, UB, UBM, CNRS, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, UPN, ArScAn, UP1, UP8, UPN, MCC, CNRS, ArchMondeGr-SI, ArScAn, UP1, UP8, UPN, MCC, CNRS
Direct litter interference and indirect soil competitive effects of two contrasting phenotypes of a spiny legume shrub drive the forb composition of an oromediterranean community
Contrasting phenotypes of foundation species are known to differentially affect understorey plants. However, there is little knowledge on both the mechanisms of competition (resource competition versus interference) of stress-tolerant phenotypes and the importance of indirect interactions. In an oromediterranean community from Mount Lebanon we assessed the effects on understorey forbs of two contrasting phenotypes, a tight competitive from stressful habitat and a loose facilitative from more benign habitat. In a dry south and a wet north exposure we assessed short-term resource effects removing shrub canopy and long-term soil effects (including litter interference) with the comparison of forb performances in adjacent naturally open areas vs no shrub. Indirect effects were quantified through the removal of grasses. Abundance, richness and biomass of forbs were measured in all treatments after one year of experiment, together with litter depth and soil moisture. We found strong direct negative soil effects of the tight phenotype on all forb performances and in particular in south exposure. These effects were due to litter interference on water availability, but not to resource competition. They were likely explained by the high hydrophobicity of organic matter accumulating in the stressful habitat of the tight phenotype. We also found an indirect competition of the loose phenotype for forb richness, due to its direct positive soil effect on competitive grasses, and in particular in south exposure. Our results improve our knowledge on the importance of litter interference in dry nutrient-poor habitats and the role of indirect interactions in phenotypic effects on understorey species.
(Oikos. vol. 126, n° 0030-1299, pp. 1090-1100, 01/02/2017)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Holocene paleoceanography of the Bay of Biscay: Evidence for west-east linkages in the North Atlantic based on dinocyst data
Paleoceanographical changes during the Holocene were reconstructed from the study of core MD95-2002 situated in the northern Bay of Biscay, which is marked by the direct influence of the northeastern return branch of the North Atlantic Drift. Palynological data, sea-surface condition estimates based on dinocyst assemblages and stable isotope measurements in planktic and benthic foraminifera reveal a strong influence of freshwater/meltwaters from both the proximal European sources and the more distal Laurentide Ice Sheet, which experienced delayed deglaciation. The data also indicate the setting of a climate optimum between 7 and 5.5 ka followed by a cooling trend, which is consistent with insolation changes and other regional records of climate changes. Superimposed on the long term trends, the reconstructions of sea-surface conditions evidence large amplitude changes at centennial to millennial time-scales, with seven episodes of cooling and low salinity since 11 ka that generally match episodes of dense sea-ice cover in the Labrador Sea. The west to east transfer of the sea-ice and/or meltwater signal across the North Atlantic evidenced from core MD95-2002 points to strong linkages between western and eastern North Atlantic, probably in relation to the North Atlantic Oscillation (NAO) mode of variability.
(Palaeogeography, Palaeoclimatology, Palaeoecology. vol. 468, n° 0031-0182, pp. 403-413, 01/02/2017)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Occurrence of antibiotics in rural catchments
(Chemosphere. vol. 168, n° 0045-6535, pp. 483-490, 01/02/2017)
METIS, EPHE, PSL, INSU - CNRS, SU, CNRS, HCMUT, VNU-HCM, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS
Earthquake-triggered deposits in the subduction trench of the north Ecuador/south Colombia margin and their implication for paleoseismology
The north Ecuador/south Colombia convergent margin is affected by recurrent subduction earthquakes with magnitudes > 7.5, like the 1906, 1942, 1958, 1979 and 2016 events. The subduction trench is characterized by the construction of the Esmeraldas Turbidite System (ETS) fed by the large Esmeraldas Canyon that deeply incises the continental slope and that connects directly onshore with the Esmeraldas River. The detailed description of cores collected in the left-hand (western) proximal levee of the ETS and in two lobes allowed discriminating two types of coarse-grained deposits: (1) “classical” flood-generated turbidites are normally graded beds with structureless, laminated and cross-laminated intervals and high organic-matter content, while (2) earthquake-induced deposits consist of amalgamated normally-graded laminated/cross-laminated intervals separated by erosive surfaces. These latter are interpreted to be deposited by quasi-synchronous flows generated during a single earthquake. Organic matter is absent in such beds while ferromagnesian minerals and pumices are abundant, suggesting remobilization of the slope deposits. When two amalgamated beds are superimposed, the interbedded clayey interval is not bioturbated, suggesting a short time period between the beds deposition, and thus the impact of a major earthquake shock and following earthquakes on the triggering of landslides. Along the ETS, core-to-core correlation based on 210Pb excess revealed that 20th Century sedimentation occurred mainly in the proximal levee. There, a temporal relationship was established between the 1906, 1942, and 1979 earthquakes, and three coarse-grained beds showing features of earthquake-induced turbidites, suggesting the Esmeraldas Canyon was the main source for sediments to be remobilized during these earthquakes. The fining and thinning observed between the 1906, 1942 and 1979 turbidites correlate with the increasing distance of the rupture zone of each earthquake with the Esmeraldas Canyon. Earthquakes with magnitudes lower than 7 also affected the margin during the 20th Century but were not recorded in the trench sedimentation, suggesting that the turbidite levee acts as a natural filter so that potentially the highest the levee the strongest the earthquake magnitude recorded. At least ten earthquakes with the highest magnitudes were recorded on the turbidite levee within the last 800 years with a recurrence time ranging from about 268 years to 42–82 years, or less for the 20th Century earthquakes. The comparison of the main features of the 1906 turbidite with older earthquake-triggered turbidites identified in a core collected in the trench suggests that one or two earthquakes similar to the 1906 event might have occurred ~ 600 years ago.
(Marine Geology. vol. 384, n° 0025-3227, pp. 47 - 62, 01/02/2017)
GEOAZUR 6526, IRD, UPMC, UNS, INSU - CNRS, UniCA, CNRS, GEOAZUR 7329, INSU - CNRS, UniCA, CNRS, IRD [Occitanie], IRD, UniCA, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, UPMC
Storm-induced marine flooding: Lessons from a multidisciplinary approach
There is a growing interest for marine flooding related to recent catastrophic events and their unintended consequences in terms of casualties and damages, and to the increasing population and issues along the coasts in a context of changing climate. Consequently, the knowledge on marine flooding has progressed significantly for the last years and this review, focused on storm-induced marine submersions, responds to the need for a synthesis. Three main components are presented in the review: (1) a state-of-the-art on marine submersions from the viewpoint of several scientific disciplines; (2) a selection of examples demonstrating the added value of interdisciplinary approaches to improve our knowledge of marine submersions; (3) a selection of examples showing how the management of future crises or the planning efforts to adapt to marine submersions can be supported by new results or techniques from the research community. From a disciplinary perspective, recent progress was achieved with respect to physical processes, numerical modeling, the knowledge of past marine floods and vulnerability assessment. At a global scale, the most vulnerable coastal areas to marine flooding with high population density are deltas and estuaries. Recent and well-documented floods allow analyzing the vulnerability parameters of different coastal zones. While storm surges can nowadays be reproduced accurately, the modeling of coastal flooding is more challenging, particularly when barrier breaches and wave overtopping have to be accounted for. The chronology of past marine floods can be reconstructed combining historical archives and sediment records. Sediment records of past marine floods localized in back barrier depressions are more adequate to reconstruct past flooding chronology. For the two last centuries, quantitative and descriptive historical data can be used to characterize past marine floods. Beyond providing a chronology of events, sediment records combined with geochronology, statistical analysis and climatology, can be used to reconstruct millennial-scale climate variability and enable a better understanding of the possible regional and local long-term trends in storm activity. Sediment records can also reveal forgotten flooding of exceptional intensity, much more intense than those of the last few decades. Sedimentological and historical archives, combined with high-resolution topographic data or numerical hindcast of storms can provide quantitative information and explanations for marine flooding processes. From these approaches, extreme past sea levels height can be determined and are very useful to complete time series provided by the instrumental measurements on shorter time scales. In particular, historical data can improve the determination of the return periods associated with extreme water levels, which are often inaccurate when computed based on instrumental data, due to the presence of gaps and too short time-series. Long-term numerical hindcast of tides and surges can also be used to provide the required time series for statistical analysis. Worst-case scenarios, used to define coastal management plans and strategies, can be obtained from realistic atmospheric settings with different tidal ranges and by shifting the trajectory of storms. Management of future crises and planning efforts to adapt to marine submersions are optimized by predictions of water levels from hydrodynamic models. Such predictions combined with in situ measurements and analysis of human stakes can be used to define a vulnerability index. Then, the efficiency of adaptation measures can be evaluated with respect to the number of lives that could be potentially saved. Numerical experiments also showed that the realignment of coastal defenses could result in water level reduction up to 1 m in the case where large marshes are flooded. Such managed realignment of coastal defenses may constitute a promising adaptation to storm-induced flooding and future sea level rise. From a legal perspective, only a few texts pay specific attention to the risk of marine flooding whether nationally or globally. Recent catastrophic events and their unintended consequences in terms of death and damages have triggered political decisions, like in USA after hurricane Katrina, and in France after catastrophic floods that occurred in 2010.
(Earth-Science Reviews. vol. 165, n° 0012-8252, pp. 151 - 184, 01/02/2017)
LIENSs, INSU - CNRS, ULR, CNRS, LNEC, ISMAR, ISMAR, CNR, EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, INSU - CNRS, UM, CNRS, UA, CEJEP, ULR, LETG - Nantes, UNICAEN, NU, EPHE, PSL, UBO EPE, UR2, CNRS, IGARUN, UN, LETG - Brest, LETG, UNICAEN, NU, UA, EPHE, PSL, UBO EPE, UR2, CNRS, IGARUN, UN, CRIHAM [Limoges, Poitiers], UP, IR SHS UNILIM, UNILIM, MSHS de Poitiers [Maison des sciences de l'homme et de la société de Poitiers], UP, CNRS, SHOM, BRGM
Gas- and particle-phase products from the photooxidation of acenaphthene and acenaphthylene by OH radicals
This work is focused on the gas-phase oxidation of acenaphthylene and acenaphthene by OH radicals and associated secondary organic aerosol (SOA) formation under low and high-NOx conditions. Experiments were carried out in an atmospheric simulation chamber using a proton transfer reaction time-of-flight-mass spectrometer (PTR-TOF-MS) and an aerosol time-of-flight-mass spectrometer (ATOFMS) to chemically characterize the gas- and particle-phase products, respectively. Due to the structures of these two aromatic compounds, the proposed chemical mechanisms exhibit some differences. In the case of acenaphthene, H-atom abstraction from the saturated cyclopenta-fused ring was found to be competitive with the OH-addition to the aromatic rings. During the photooxidation of acenaphthene using nitrous acid (HONO), aromatic ring-opening products such as indanone and indanone carbaldehyde, generated through OH addition to the aromatic ring, were formed in higher yields compared to low-NOx conditions. In the case of acenaphthylene, OH addition to the unsaturated cyclopenta-fused ring was strongly favored. Hence, ring-retaining species such as acenaphthenone and acenaphthenequinone, were identified as the main reaction products in both gas- and particle-phases, especially under high-NOx conditions. Subsequent SOA formation was observed in all experiments and SOA yields were determined under low/high-NOx conditions to be 0.61/0.46 and 0.68/0.55 from the OH-initiated oxidation of acenaphthylene and acenaphthene, respectively.
(Atmospheric Environment. vol. 151, n° 1352-2310, pp. 34-44, 01/02/2017)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, UCC
The open sea as the main source of methylmercury in the water column of the Gulf of Lions (Northwestern Mediterranean margin)
Despite the ecologic and economical importance of coastal areas, the neurotoxic bioaccumulable monomethylmercury (MMHg) fluxes within the ocean margins and exchanges with the open sea remain unassessed. The aim of this paper is to address the questions of the abundance, distribution, production and exchanges of methylated mercury species (MeHgT), including MMHg and dimethylmercury (DMHg), in the waters, atmosphere and sediments of the Northwestern Mediterranean margin including the Rhône River delta, the continental shelf and its slope (Gulf of Lions) and the adjacent open sea (North Gyre).
(Geochimica et Cosmochimica Acta, n° 0016-7037, 01/02/2017)
EPOC, EPHE, PSL, UB, INSU - CNRS, CNRS, CEFREM, UPVD, INSU - CNRS, CNRS, OOB, UPMC, CNRS